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Translational Toxicology Defining a New Therapeutic Discipline /

Bringing together a distinguished interdisciplinary team of contributors, this volume provides a comprehensive exploration of translational toxicology-a systematic approach to developing therapeutic interventions that can protect against, mitigate, or reverse the effects of exposures. In particular,...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hughes, Claude L. (Editor ), Waters, Michael D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:Molecular and Integrative Toxicology,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • I.Introduction
  • The Opportunity to Translate Developmental Toxicology into a Therapeutic Discipline
  • The Role of Toxicokinetics and Toxicodynamics in Developmental and Translational Toxicology
  • II.Toxicant Modes of Action and Biomarkers
  • Mutational Effects
  • Ligand-Mediated Toxicology: Characterization and Translational Prospects
  • Effects of Environmentally Acquired Heavy Metals and Nutrients on the Epigenome and Phenotype
  • Fetal Imaging and Effects of Exposures on Growth and Function
  • III.Developmental Risks of Exposures and Potential Translational Toxicology Therapeutics
  • Ovarian Toxicity of Environmental Contaminants: 50 Shades of Grey
  • The "Toxic" Effects of a Perinatal Obesogenic Environment: Maternal Obesity and Impacts on Future Generations
  • The Role of Environmental Exposures in Preterm Birth
  • The Impact of Environmental Stressors on DNA Methylation, Neurobehavioral Development and Chronic Physical Aggression: Prospects for Early Protective Interventions
  • Coffee Health Effects from Early Fetal Development through Childhood and Adolescence.