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Myeloid-Derived Suppressor Cells and Cancer

The book starts with an introduction to and history of myeloid-derived suppressor cells (MDSCs), followed by a description of their differentiation, their role in the tumour microenvironment and their therapeutic targeting. It closes with an outlook on future developments. In cancer patients, myelop...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Escors, David (Autor), Talmadge, James E. (Autor), Breckpot, Karine (Autor), Van Ginderachter, Jo A. (Autor), Kochan, Grazyna (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:SpringerBriefs in Immunology,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Controversies in Neoplastic Myeloplasia
  • Differentiation of Murine Myeloid-derived Suppressor Cells
  • Human MDSCs
  • Ex Vivo MDSC Differentiation Models
  • Immunoregulatory myeloid cells in the tumor microenvironment
  • Signal Transducer and Activation of Transcription 3: A Master Regulator of Myeloid-derived Suppressor Cells
  • Future Perspectives.