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Clinical Trials of Antidepressants How Changing the Model Can Uncover New, More Effective Molecules /
This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the compo...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | SpringerBriefs in Psychology,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Why Now the Need for a New Clinical Trial Model for Antidepressants?
- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials
- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models
- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach
- The Component-Specific Model Applied in a Clinical Trial: An Example
- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial
- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model
- The Video Clinical Trial and the VIBES Method
- Conclusions.