B Cell Receptor Signaling

This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions foc...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Kurosaki, Tomohiro (Editor ), Wienands, Jürgen (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Current Topics in Microbiology and Immunology, 393
Temas:
Immunology.
Medicine > Research.
Biology > Research.
Cancer.
Biomedical Research.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Assembly and function of the precursor B-cell receptor
  • Receptor Dissociation and B cell activation
  • Molecular mechanisms of B cell antigen gathering and endocytosis
  • BTK signaling in B cell differentiation and autoimmunity
  • The memory function of the B cell antigen receptor
  • PI3K signaling in normal B cells and chronic lymphocytic leukemia (CLL)
  • Role of Calcium Signaling in B Cell Activation and Biolog
  • Roles of the NF-kappaB pathway in B-lymphocyte biology
  • MAP kinase cascades in antigen receptor signaling and physiology.

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