Surface-Enhanced Raman Spectroscopy Bioanalytical, Biomolecular and Medical Applications /

This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limit...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Prochazka, Marek (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Biological and Medical Physics, Biomedical Engineering,
Temas:
Biophysics.
Biology-Technique.
Spectrum analysis.
Measurement.
Measuring instruments.
Medical physics.
Biological Techniques.
Spectroscopy.
Measurement Science and Instrumentation.
Medical Physics.
Acceso en línea:Texto Completo
Descripción
Sumario:This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
Descripción Física:XVI, 221 p. 78 illus., 27 illus. in color. online resource.
ISBN:9783319239927
ISSN:2197-5647

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