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Understanding Kidney Diseases
This book provides the essential understanding needed for the assessment of patients with kidney disease. The chapters follow the sequence taken during a clinic consultation and when clerking a patient. At each stage, the principles and concepts underlying aspects of renal medicine that may seem dif...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- The purpose of the book - understanding the natural history of kidney disease
- how displaying a GFR history is a fundamental part of the clinical assessment of kidney diseases
- how the eGFR graph is used to inform patients and plan treatment.-principles but not details of treatment
- The basics of creatinine measurement and eGFR equations in adults
- Simple guide to the classification of AKI, AKD and CKD
- Stages of CKD - including proteinuria
- The meaning of 'stability' in an eGFR graph - variation over time
- Cases
- Section 1: Acute kidney injury - changes over 50% drop, assuming no asymmetry)
- Recurrent AKI leading to CKD
- Section 2: AKD - changes >48 hours 3months
- Patterns of progression - Linear and Non-linear
- Monitoring response to treatment - e.g. immunosuppression for GN, BP control in malignant hypertension
- Section 4: CKD - changes over years
- non-progressive (stable) CKD - e.g. obstructive uropathy
- progressive CKD - e.g. transplant nephropathy, lithium nephrotoxicity, role of proteinuria as risk marker
- Use of graphs to plan future renal replacement therapy - e.g. linear progression in ADPKD
- Section 5: Acute-on-chronic kidney disease
- Chronic slowly progressive diabetic nephropathy with superimposed acute pathology, e.g. response to ACEI/ARB, contrast nephropathy, glomerulonephritis, interstitial nephritis
- Transplant rejection
- Pregnancy in women with CKD
- Section 6: Nephrotic syndrome
- GFR, serum albumin and urinary PCR graphs - use to monitor treatment and relapses, and to plan treatment
- Section 7: Other graphs
- 24 hour BP measurement - importance of nocturnal dip and timing of antihypertensives in CKD care
- Diabetes mellitus - HbA1c - colour coding as patient education tool; role of glucose control in preventing diabetic nephropathy (but no impact once CKD established)
- Serum free light chains and myeloma kidney/light chain nephropathy/immune GN
- Conclusions
- eGFR graphs - an essential tool in patient assessment which tells the story of kidney disease
- The role of graphs (eGFR, 24 hour BP, and HbA1c) in patient education and support of self-management
- Role of eGFR graphs in systematic CKD surveillance by renal units and pathology labs - evidence of benefit.