Cargando…
Structure Determination of HIV-1 Tat/Fluid Phase Membranes and DMPC Ripple Phase Using X-Ray Scattering
This Thesis in biological physics has two components, describing the use of X-ray scattering techniques to study the structure of two different stacked lipid membrane systems. The first part focuses on the interaction between a short 11-mer peptide, Tat, which is part of the Tat protein in the HIV-...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
|
| Edición: | 1st ed. 2015. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
|
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction
- Lipid bilayers
- Tat peptide
- Pb¢ ripple phase
- Structural and Material Perturbations of Lipid Bilayers Due to HIV-1 Tat Peptide
- Introduction
- Materials and Methods
- Analysis of Molecular Dynamics Simulation Data
- Results
- Discussion
- Conclusions
- Ripple Phase
- Introduction
- Materials and Methods
- LAXS Data Reduction
- Results for Fhk Form Factors
- Models to Fit the Fhk and Obtain the Phase Factors
- Electron Density Profiles and Coarse Grained Bilayer Structure
- nGIWAXS: Results
- tWAXS: Results
- Thin Rod Model
- Combining WAXS and LAXS Results for the Major Arm
- Discussion
- Conclusion
- Appendices.