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Computational Modelling of the Human Islet Amyloid Polypeptide
This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2016.
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| Edición: | 1st ed. 2016. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-3-319-20040-8 | ||
| 003 | DE-He213 | ||
| 005 | 20220114202524.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 160527s2016 sz | s |||| 0|eng d | ||
| 020 | |a 9783319200408 |9 978-3-319-20040-8 | ||
| 024 | 7 | |a 10.1007/978-3-319-20040-8 |2 doi | |
| 050 | 4 | |a RS400-431 | |
| 072 | 7 | |a PNN |2 bicssc | |
| 072 | 7 | |a PSB |2 bicssc | |
| 072 | 7 | |a SCI013020 |2 bisacsh | |
| 072 | 7 | |a PNB |2 thema | |
| 082 | 0 | 4 | |a 615.19 |2 23 |
| 100 | 1 | |a Skeby, Katrine Kirkeby. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Computational Modelling of the Human Islet Amyloid Polypeptide |h [electronic resource] / |c by Katrine Kirkeby Skeby. |
| 250 | |a 1st ed. 2016. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2016. | |
| 300 | |a XVI, 118 p. 58 illus., 47 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 505 | 0 | |a Amyloid and Amyloid Fibrils -- Computational Theory -- Imaging Agent Binding to Amyloid Protofibrils -- Determining the Aggregation Prone Structure of hiAPP -- Effect of Terminal Capping on Aggregation of Peptide Fragments -- Coarse Grained Study of Amyloid Protofibril Aggregation -- Conclusion and Perspectives. | |
| 520 | |a This thesis offers readers a comprehensive introduction to amyloid proteins and the computational methods used with them. Katrine Skeby critically assesses and compares both the literature and the experiments performed by other researchers, which further elevates the quality and relevance of her own work. Amyloid proteins are highly complex, and this research provides unparalleled insights, especially with regard to the origin of cytotoxicity and to developing technologies for early detection, revealing in detail the molecular mechanisms behind hIAPP behavior. Several studies within the thesis answer difficult questions which promote future research into the properties of amyloid proteins. | ||
| 650 | 0 | |a Medicinal chemistry. | |
| 650 | 0 | |a Chemistry-Data processing. | |
| 650 | 0 | |a Bioorganic chemistry. | |
| 650 | 1 | 4 | |a Medicinal Chemistry. |
| 650 | 2 | 4 | |a Computational Chemistry. |
| 650 | 2 | 4 | |a Bioorganic Chemistry. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783319200392 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319200415 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319792934 |
| 830 | 0 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-319-20040-8 |z Texto Completo |
| 912 | |a ZDB-2-CMS | ||
| 912 | |a ZDB-2-SXC | ||
| 950 | |a Chemistry and Materials Science (SpringerNature-11644) | ||
| 950 | |a Chemistry and Material Science (R0) (SpringerNature-43709) | ||