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The Neuropathology of Huntington's Disease: Classical Findings, Recent Developments and Correlation to Functional Neuroanatomy
This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldw...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edición: | 1st ed. 2015. |
| Colección: | Advances in Anatomy, Embryology and Cell Biology,
217 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- 1. Introduction
- 2. The neuropathological grading of Huntington disease
- 3. The cerebral cortex in Huntington´s disease
- 4. Degeneration of select motor and limbic nuclei of the thalamus in Huntington's disease
- 5. Consistent and widespread degeneration of the cerebellum in Huntington's disease
- 6. Elucidation of the role of the premotor oculomotor brainstem nuclei in the pathogenesis of oculomotor dysfunctions in Huntington's disease
- 7. Widespread brainstem neurodegeneration in Huntington's disease
- 8. Intraneuronal transport and defense mechanisms with possible pathogenetic relevance in Huntington's disease
- 9. The disease protein huntingtin and neuronal protein aggregations in Huntington's disease
- 10. Pathological nerve cell alterations in Huntington's disease (HD) and their possible role for the demise of nerve cells
- 11. Conclusions and outlook.