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Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative disease...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Vassallo, Neville (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Experimental Medicine and Biology, 863
Temas:
Acceso en línea:Texto Completo

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245 1 0 |a Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases  |h [electronic resource] /  |c edited by Neville Vassallo. 
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490 1 |a Advances in Experimental Medicine and Biology,  |x 2214-8019 ;  |v 863 
505 0 |a Olive Oil Phenols as Promising Multi-targeting Agents against Alzheimer's disease -- Alzheimer's disease, Drosophila melanogaster and Polyphenols -- Biflavonoids as Potential Small Molecule Therapeutics for Alzheimer's disease -- Natural Phenolic Compounds as Therapeutic and Preventive Agents for Cerebral Amyloidosis.- Brain Food for Alzheimer-free Ageing: Focus on Herbal Medicines -- Tea Polyphenols in Parkinson's disease -- The Effect of (-)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. 
520 |a This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed 'amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents. This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders. Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others. The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry. 
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650 0 |a Nutrition   . 
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