Histone Recognition

This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader doma...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Zhou, Ming-Ming (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Molecular genetics.
Post-translational modification.
Proteins .
Medical genetics.
Molecular Genetics.
Post-translational Modifications.
Protein Biochemistry.
Medical Genetics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Bromodomain as the Acetyl-Lysine Binding Domain in Gene Transcription
  • PHD Fingers as Histone Readers
  • Methyl-Lysine Recognition by the Royal Family Modules: Chromo, Tudor, MBT, Chromo Barrel, and PWWP Domains
  • Histone Recognition by WD40 Proteins
  • Methyl-Lys Recognition by Ankyrin Repeat Proteins
  • Methyl-Arginine Recognition by Tudor Domains
  • Histone Recognition by Tandem Modules and Modulation by Multiple PTMs
  • Genome-Wide Profiling of Molecular Recognition of Histone PTMs
  • BET Bromodomain Inhibition as a Therapeutic Approach in Hematological Malignancies
  • Anti-Inflammatory Effects of BET Protein Inhibition Through Modulation of Gene Transcription
  • Activating Latent HIV by Inhibiting Bromodomain Proteins
  • Small Molecule Modulation of Methyl-Lysine Mediated Interactions.

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