Cardiac Fibrosis and Heart Failure: Cause or Effect?

The unique biology of cardiac fibroblasts and related cells, such as cardiac myofibroblasts and valvular interstitial cells, distinguish them from other fibroblastic cells, a concept that is only beginning to be widely appreciated.  Further, the natural signals that stimulate and inhibit cardiac fib...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dixon, Ian M.C (Editor ), Wigle, Jeffrey T. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Biochemistry in Health and Disease, 13
Temas:
Cytology.
Cardiology.
Medicine-Research.
Biology-Research.
Cell Biology.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • 1. Fibrosis and Heart Failure - Cause or Effect?
  • 2. Fibroblast Activation in the Infarcted Myocardium
  • 3. Mechanical and Matrix Regulation of Valvular Fibrosis
  • 4. Bone Marrow-Derived Progenitor Cells, micro-RNA and Fibrosis
  • 5. The Stressful Life of Cardiac Myofibroblasts
  • 6. Pathogenic Origins of Fibrosis in the Hypertensive Heart Disease that Accompanies Aldosteronism
  • 7. Embryological origin of valve progenitor cells
  • 8. Diverse cellular origins of cardiac fibroblasts
  • 9. Non-Canonical Regulation of TGF-β1 Signaling: A Role for Ski/Sno and YAP/TAZ
  • 10. Molecular mechanisms of smooth muscle and fibroblast phenotype conversions in the failing heart
  • 11. Current and future strategies for the diagnosis and treatment of cardiac fibrosis
  • 12. Remodelling of the cardiac extracellular matrix:  Role of collagen degradation and accumulation in  pathogenesis of heart failure
  • 13. Matrix Metalloproteinase 9 (MMP-9): The Middle-Man of Post Myocardial Infarction Extracellular Matrix Remodelling
  • 14. Collagen processing and its role in Fibrosis
  • 15. Mechanisms of Cardiac Fibrosis
  • 16. Mathematical Simulations of Sphingosine-1-Phosphate Actions on Mammalian Ventricular Myofibroblasts and Myocytes
  • 17. Extracellular Matrix and Cardiac Disease: Surgical and Scientific Perspectives
  • 18. The Role of Neurohumoral Activation in Cardiac Fibrosis and Heart Failure
  • 19. Natriuretic peptides: critical regulators of cardiac fibroblasts and the extracellular matrix in the heart
  • 20. Cardiac Tissue Engineering for the Treatment of Heart Failure Post-Infarction
  • 21. Mechanisms of Cardiac Valve Failure and the Development of Tissue Engineered Heart Valves.

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