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Lipids in Protein Misfolding

This book addresses molecular mechanisms of protein misfolding and the role of lipids and related molecules in these complex processes. The focus is on the biophysical and structural studies of proteins that are involved in major human disorders such as Alzheimer's disease, systemic amyloidoses...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gursky, Olga (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Experimental Medicine and Biology, 855
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins
  • Protein Misfolding in Lipid-Mimetic Environments.- Lipids in Amyloid-β Processing, Aggregation, and Toxicity
  • Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloidosis
  • Stability, Oligomerization, and Amyloidogenicity of Apo Serum Amyloid A
  • Interactions of Lipid Membranes with Fibrillar Protein Aggregates
  • The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II
  • Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights
  • Computational Approaches to Identification of Aggregation Sites and the Mechanism of Amyloid Growth
  • Role of Syndecans in Lipid Metabolism and Human Diseases.