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00000nam a22000005i 4500 |
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978-3-319-17305-4 |
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150610s2015 sz | s |||| 0|eng d |
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|a 9783319173054
|9 978-3-319-17305-4
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|a 10.1007/978-3-319-17305-4
|2 doi
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|a RB155-155.8
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|a MFN
|2 bicssc
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|a MED107000
|2 bisacsh
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|a MFN
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|a 616.042
|2 23
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|a RNA and DNA Diagnostics
|h [electronic resource] /
|c edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski.
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|a 1st ed. 2015.
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|a Cham :
|b Springer International Publishing :
|b Imprint: Springer,
|c 2015.
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|a X, 349 p. 124 illus., 78 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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|a RNA Technologies,
|x 2197-9758
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|a Electrochemical Biosensors for miRNA Detection -- Electrochemical Detection of RNA.- DNA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing.- Microarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics.- Single-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease.
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|a The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman's famous statement "What I cannot create, I do not understand.".
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|a Medical genetics.
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|a Biomaterials.
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|a Nucleic acids.
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650 |
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|a Medicine
|x Research.
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|a Biology
|x Research.
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|a Biotechnology.
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|a Medical Genetics.
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|a Nucleic Acid.
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|a Biomedical Research.
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|a Biotechnology.
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|a Erdmann, Volker A.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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1 |
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|a Jurga, Stefan.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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700 |
1 |
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|a Barciszewski, Jan.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
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|t Springer Nature eBook
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776 |
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|i Printed edition:
|z 9783319173061
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776 |
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|i Printed edition:
|z 9783319173047
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776 |
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|i Printed edition:
|z 9783319361994
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830 |
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|a RNA Technologies,
|x 2197-9758
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|u https://doi.uam.elogim.com/10.1007/978-3-319-17305-4
|z Texto Completo
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|a ZDB-2-SBL
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|a ZDB-2-SXB
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|a Biomedical and Life Sciences (SpringerNature-11642)
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|a Biomedical and Life Sciences (R0) (SpringerNature-43708)
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