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Pre-Analytics of Pathological Specimens in Oncology

This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pat...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dietel, Manfred (Editor ), Wittekind, Christian (Editor ), Bussolati, Gianni (Editor ), Winterfeld, Moritz (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Recent Results in Cancer Research, 199
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Pre-Analytics of Pathological Specimens in Oncology  |h [electronic resource] /  |c edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld. 
250 |a 1st ed. 2015. 
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300 |a VI, 133 p. 65 illus., 61 illus. in color.  |b online resource. 
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490 1 |a Recent Results in Cancer Research,  |x 2197-6767 ;  |v 199 
505 0 |a What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics - Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge.  . 
520 |a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up. 
650 0 |a Oncology. 
650 0 |a Pathology. 
650 0 |a Surgery. 
650 0 |a Medicine  |x Research. 
650 0 |a Biology  |x Research. 
650 1 4 |a Oncology. 
650 2 4 |a Pathology. 
650 2 4 |a Surgery. 
650 2 4 |a Biomedical Research. 
700 1 |a Dietel, Manfred.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Wittekind, Christian.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Bussolati, Gianni.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Winterfeld, Moritz.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
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