IgE Antibodies: Generation and Function

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Lafaille, Juan J. (Editor ), Curotto de Lafaille, Maria A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Current Topics in Microbiology and Immunology, 388
Temas:
Immunospecificity.
Medicine > Research.
Biology > Research.
Allergy.
Parasitology.
Adaptive Immunity.
Biomedical Research.
Allergology.
Acceso en línea:Texto Completo
Descripción
Sumario:This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.
Descripción Física:IX, 152 p. 21 illus., 16 illus. in color. online resource.
ISBN:9783319137254
ISSN:2196-9965 ;

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