Neuroanatomy and Pathology of Sporadic Alzheimer's Disease

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. T...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Braak, Heiko (Autor), Del Tredici, Kelly (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Anatomy, Embryology and Cell Biology, 215
Temas:
Neurosciences.
Pathology.
Geriatrics.
Neuroscience.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Prologue
  • General Morphology of Alzheimer-associated intraneuronal pathology
  • Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible
  • Basic organization of involved structures
  • Presymptomatic stages
  • General morphology of Alzheimer-associated extracellular pathology
  • Symptomatic stages
  • The progression of cortical lesions mimics the pattern of myelination in reverse order
  • Tauopathies
  • CSF biomarkers and imaging techniques
  • The staging hypothesis: assumptions, challenges, potential
  • Technical considerations.   .

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