Neuroanatomy and Pathology of Sporadic Alzheimer's Disease

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. T...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Braak, Heiko (Autor), Del Tredici, Kelly (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Colección:Advances in Anatomy, Embryology and Cell Biology, 215
Temas:
Neurosciences.
Pathology.
Geriatrics.
Neuroscience.
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-3-319-12679-1
003 DE-He213
005 20220117185157.0
007 cr nn 008mamaa
008 141211s2015 sz | s |||| 0|eng d
020 |a 9783319126791  |9 978-3-319-12679-1 
024 7 |a 10.1007/978-3-319-12679-1  |2 doi 
050 4 |a RC321-580 
072 7 |a PSAN  |2 bicssc 
072 7 |a MED057000  |2 bisacsh 
072 7 |a PSAN  |2 thema 
082 0 4 |a 612.8  |2 23 
100 1 |a Braak, Heiko.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Neuroanatomy and Pathology of Sporadic Alzheimer's Disease  |h [electronic resource] /  |c by Heiko Braak, Kelly Del Tredici. 
250 |a 1st ed. 2015. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2015. 
300 |a XI, 162 p. 48 illus., 44 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Advances in Anatomy, Embryology and Cell Biology,  |x 2192-7065 ;  |v 215 
505 0 |a Prologue -- General Morphology of Alzheimer-associated intraneuronal pathology -- Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible -- Basic organization of involved structures -- Presymptomatic stages -- General morphology of Alzheimer-associated extracellular pathology -- Symptomatic stages -- The progression of cortical lesions mimics the pattern of myelination in reverse order -- Tauopathies -- CSF biomarkers and imaging techniques -- The staging hypothesis: assumptions, challenges, potential -- Technical considerations.   . 
520 |a As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail. 
650 0 |a Neurosciences. 
650 0 |a Pathology. 
650 0 |a Geriatrics. 
650 1 4 |a Neuroscience. 
650 2 4 |a Pathology. 
650 2 4 |a Geriatrics. 
700 1 |a Del Tredici, Kelly.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783319126784 
776 0 8 |i Printed edition:  |z 9783319126807 
830 0 |a Advances in Anatomy, Embryology and Cell Biology,  |x 2192-7065 ;  |v 215 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-3-319-12679-1  |z Texto Completo 
912 |a ZDB-2-SME 
912 |a ZDB-2-SXM 
950 |a Medicine (SpringerNature-11650) 
950 |a Medicine (R0) (SpringerNature-43714) 

Ejemplares similares