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Genomic Instability and Cancer Metastasis Mechanisms, Emerging Themes, and Novel Therapeutic Strategies /
Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner....
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edición: | 1st ed. 2015. |
| Colección: | Cancer Metastasis - Biology and Treatment,
20 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Preface.- Cancer Metastasis: Tracking and Attacking a Moving Target.- The generation, detection, and prevention of genomic instability during cancer progression and metastasis.- DNA damage response pathways in cancer predisposition and progression.- Mathematical modeling for DNA repair, carcinogenesis and cancer detection.- Animal models of metastasis.- Microenvironmental Control Of Metastatic Progression.- 7 Mechanotransduction, metastasis and genomic instability
- 8 Immunomodulation and Genomic Instability
- 9 Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
- Nanomedicine - Nanoparticles in Cancer Imaging and Therapy
- Index.