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DNA Replication Control in Microbial Cell Factories
This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition,...
| Clasificación: | Libro Electrónico |
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| Autores principales: | , , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing : Imprint: Springer,
2015.
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| Edición: | 1st ed. 2015. |
| Colección: | SpringerBriefs in Microbiology,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Introduction.- Coordinating duplication of genetic material with cell growth - current views and old questions.- Structural organization of cellular processes and the regulation of cell cycle
- The link between metabolism and DNA replication
- Transcriptional activation - the unsolved problem
- Activity of DnaA is inhibited by components of translation machinery
- Nucleoid-associated proteins modulate activity of the DnaA initiator
- Interaction of DnaA with acidic components of fluid cellular membrane regulates its nucleotide-bound status and binding to oriC
- Influence of DNA replication on cell structure and function
- Conclusions.