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High-Performance Computational Solutions in Protein Bioinformatics

Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation leve...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Mrozek, Dariusz (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:SpringerBriefs in Computer Science,
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a High-Performance Computational Solutions in Protein Bioinformatics  |h [electronic resource] /  |c by Dariusz Mrozek. 
250 |a 1st ed. 2014. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2014. 
300 |a XIX, 109 p. 56 illus., 21 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
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505 0 |a Formal Model of 3D Protein Structures for Functional Genomics, Comparative Bioinformatics, and Molecular Modeling -- Multithreaded PSS-SQL for Searching Databases of Secondary Structures -- GPU and CUDA for 3D Protein Structure Similarity Searching -- Cloud Computing for 3D Protein Structure Alignment -- General Discussion and Concluding Remarks. 
520 |a Recent developments in computer science enable algorithms previously perceived as too time-consuming to now be efficiently used for applications in bioinformatics and life sciences. This work focuses on proteins and their structures, protein structure similarity searching at main representation levels, and various techniques that can be used to accelerate similarity searches. Divided into four parts, the first part provides a formal model of 3D protein structures for functional genomics, comparative bioinformatics, and molecular modeling. The second part focuses on the use of multithreading for efficient approximate searching on protein secondary structures. The third and fourth parts concentrate on finding 3D protein structure similarities with the support of GPUs and cloud computing. Parts three and four both describe the acceleration of different methods. The text will be of interest to researchers and software developers working in the field of structural bioinformatics and biomedical databases. 
650 0 |a Bioinformatics. 
650 0 |a Computer networks . 
650 0 |a Proteins. 
650 0 |a Microprocessors. 
650 0 |a Computer architecture. 
650 0 |a Biomathematics. 
650 1 4 |a Computational and Systems Biology. 
650 2 4 |a Computer Communication Networks. 
650 2 4 |a Proteins. 
650 2 4 |a Bioinformatics. 
650 2 4 |a Processor Architectures. 
650 2 4 |a Mathematical and Computational Biology. 
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