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Sickle Cell Anemia From Basic Science to Clinical Practice /

Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Costa, Fernando Ferreira (Editor ), Conran, Nicola (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Chapter 1 Hemoglobin: Structure, Synthesis and Oxygen Transport
  • Chapter 2 Sickle cell Anemia: History and Epidemiology
  • Chapter 3 Overview of Sickle Cell Anemia Pathophysiology
  • Chapter 4 Red Blood Cells and the Vaso-occlusive Process
  • Chapter 5 Leukocytes in the vaso-occlusive process
  • Chapter 6 Hypercoagulability and Sickle Cell Disease
  • Chapter 7 Cardiovascular Adaptations to Anemia and the Role of Vascular Endothelium in Sickle Cell Disease Pathophysiology
  • Chapter 8 Inflammation and Sickle Cell Anemia
  • Chapter 9 Clinical Manifestations of Sickle Cell Anemia: Infants and Children
  • Chapter 10 Treatment of Childhood Sickle Cell Disease
  • Chapter 11 Priapism in Sickle Cell Disease: New aspects of pathophysiology
  • Chapter 12 Clinical Manifestations and Treatment of Adult Sickle Cell
  • Chapter 13 Hemoglobin Sβ Thalassemia, SC Disease and SD Disease: Clinical and Laboratorial Aspects
  • Chapter 14 Sickle Cell Disease in Africa and the Arabian Peninsula: Current Management and Challenges
  • Chapter 15 Genetic Factors modifying sickle cell disease severity
  • Chapter 16 Future Perspectives for the Treatment of Sickle Cell.