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Gold-Catalyzed Cycloisomerization Reactions Through Activation of Alkynes New Developments and Mechanistic Studies /
Antoine Simonneau's thesis highlights the development of new cycloisomerization reactions through the activation of alkynes with gold complexes. First Simonneau describes 1,6-enynes and their direct conversion into allenes through 1,5-hydride or ester migration processes.The author and his team...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
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Cham :
Springer International Publishing : Imprint: Springer,
2014.
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| Edición: | 1st ed. 2014. |
| Colección: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-3-319-06707-0 | ||
| 003 | DE-He213 | ||
| 005 | 20220118035652.0 | ||
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| 008 | 140521s2014 sz | s |||| 0|eng d | ||
| 020 | |a 9783319067070 |9 978-3-319-06707-0 | ||
| 024 | 7 | |a 10.1007/978-3-319-06707-0 |2 doi | |
| 050 | 4 | |a QD410-412.5 | |
| 072 | 7 | |a PNND |2 bicssc | |
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| 072 | 7 | |a PNND |2 thema | |
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| 100 | 1 | |a Simonneau, Antoine. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Gold-Catalyzed Cycloisomerization Reactions Through Activation of Alkynes |h [electronic resource] : |b New Developments and Mechanistic Studies / |c by Antoine Simonneau. |
| 250 | |a 1st ed. 2014. | ||
| 264 | 1 | |a Cham : |b Springer International Publishing : |b Imprint: Springer, |c 2014. | |
| 300 | |a XXII, 245 p. 404 illus., 5 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 505 | 0 | |a From the Contents: General Introduction Gold, a Powerful Tool for the Activation of C-C Multiple Bonds -- Gold and Platinum-Catalyzed Reactions of Enynes -- New Advances in the Gold-Catalyzed Cycloisomerization Reactions of Enynes: 1,5-hydride Shifts and Access to Ketomacrolactones. | |
| 520 | |a Antoine Simonneau's thesis highlights the development of new cycloisomerization reactions through the activation of alkynes with gold complexes. First Simonneau describes 1,6-enynes and their direct conversion into allenes through 1,5-hydride or ester migration processes.The author and his team used appropriate propargylic functional groups to achieve this conversion. This study shows that O-tethered 1,6-enynes carrying a strained cycloalkane at the propargylic position could undergo a cyclopropanation/ring expansion cascade reaction.The author employed this rearrangement as the starting point in the design of a new macrocycle synthesis. The next part of the thesis focuses on the cycloisomerization of diynes involving as the first step of the process the rearrangement of one alkyne partner into an allene thanks to a gold-catalyzed 1,3-shift of a propargylic ester. The thesis discloses a new cycloisomerization pattern featuring a 1,5-carbonyl transfer, giving rise to unprecedented cross-conjugated diketones. In the final part of the research, Simmoneau investigates the gold-catalyzed cycloisomerization mechanism of 1,6-enynes and questions the intermediacy of gold acetylides. By the means of NMR and mass spectrometry analysis, theoretical treatment and solution experiments, it was possible to rule out the involvement of these species in the catalytic cycle. This thesis has led to a number of publications in high-impact journals. | ||
| 650 | 0 | |a Organometallic chemistry . | |
| 650 | 0 | |a Catalysis. | |
| 650 | 0 | |a Chemistry, Technical. | |
| 650 | 1 | 4 | |a Organometallic Chemistry. |
| 650 | 2 | 4 | |a Catalysis. |
| 650 | 2 | 4 | |a Industrial Chemistry. |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9783319067087 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319067063 |
| 776 | 0 | 8 | |i Printed edition: |z 9783319360973 |
| 830 | 0 | |a Springer Theses, Recognizing Outstanding Ph.D. Research, |x 2190-5061 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-3-319-06707-0 |z Texto Completo |
| 912 | |a ZDB-2-CMS | ||
| 912 | |a ZDB-2-SXC | ||
| 950 | |a Chemistry and Materials Science (SpringerNature-11644) | ||
| 950 | |a Chemistry and Material Science (R0) (SpringerNature-43709) | ||