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MicroRNA Targeted Cancer Therapy

Since the discovery of microRNAs (miRNAs) some twenty years ago by Victor Ambros, David Baulcombe and Gary Ruvkun, these three scientists worked to uncover the mystery of miRNA, the small segments of nucleotides that silence genes. While studying the development of the nematode worm, Ambros and Ruvk...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Sarkar, Fazlul H. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • The therapeutic role of microRNAs in human gliomas
  • miRNA expression and functions in glioma and glioma stem cells
  • The role of miRNAs in lung cancer drug resistance and targeted therapy
  • The Potential Role of MicroRNA-Based Therapy for Lung Cancer Stem Cells
  • State of our knowledge on miRNA targeted therapy in Lung Cancer
  • miRNA-based Ovarian Cancer Diagnosis and Therapy
  • Application of microRNA in the treatment and diagnosis of cervical cancer
  • Overcoming Drug Resistance in Colorectal Cancer by microRNAs
  • MicroRNAs as novel targets in liver cancer- facing the clinical challenge
  • MicroRNA based therapeutic strategies for cancer: Emphasis on advances in renal cell carcinoma
  • Modulating microRNA expression for the therapy of pancreatic cancer
  • MicroRNA targeted therapy for overcoming drug resistance, reversal of EMT and elimination of cancer stem cells in prostate and pancreatic cancer.- Modulation of deregulated miRNAs for targeted therapy in thyroid cancer
  • miRNA-targeted therapies in the most prevalent pediatric solid tumors
  • Targeting Immune System Through Targeting miRNA For Cancer Therapy.- miRNA regulation of DNA damage repair proteins in cancer cells: interplay of ATM, TRAIL and miRNA
  • miRNA regulation of VEGF/VEGFR signaling
  • Systems Biology Approaches in the Design of Effective miRNA-Targeted Therapeutics. Index.