Mechanisms of Atrial Arrhythmias Insights from the Development of a Biophysically Detailed Model of the Human Atria /

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac elec...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Colman, Michael A. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Cham : Springer International Publishing : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Springer Theses, Recognizing Outstanding Ph.D. Research,
Temas:
Biophysics.
Cardiology.
Bioinformatics.
Mathematical physics.
Computational and Systems Biology.
Theoretical, Mathematical and Computational Physics.
Mathematical Physics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction
  • Background
  • Development of a new model for simulating the electrical action potentials of human atrial myocytes
  • Development of a family of regional cell models
  • Autonomic regulation and pathophysiological remodelling
  • 3D Anatomical Modelling of the Atria
  • Pacemaking and autonomic regulation in the 3D sinoatrial node and atria
  • Atrial Fibrillation
  • Discussion.

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