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The Epothilones: An Outstanding Family of Anti-Tumor Agents From Soil to the Clinic /
Epothilones have received unusual attention over the past ten years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization. In comparison to paclitaxel and a number of alternative drugs with a similar mode of bioaction (e.g. laulim...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Vienna :
Springer Vienna : Imprint: Springer,
2009.
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| Edición: | 1st ed. 2009. |
| Colección: | Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products ;
90 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- General Aspects
- Biosynthesis and Heterologous Production of Epothilones
- Total Synthesis of Epothilones A-F
- Semisynthetic Derivatives of Epothilones
- Preclinical Pharmacology and Structure-Activity Studies of Epothilones
- Clinical Studies with Epothilones.