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Genomics of Pattern Recognition Receptors Applications in Oncology and Cardiovascular Diseases /

This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focu...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Kutikhin, Anton G. (Autor), Yuzhalin, Arseniy E. (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Springer Basel : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a Genomics of Pattern Recognition Receptors  |h [electronic resource] :  |b Applications in Oncology and Cardiovascular Diseases /  |c by Anton G. Kutikhin, Arseniy E. Yuzhalin. 
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300 |a XI, 185 p.  |b online resource. 
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505 0 |a The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go. 
520 |a This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed. 
650 0 |a Proteins. 
650 0 |a Immunology. 
650 0 |a Cancer. 
650 0 |a Medical genetics. 
650 0 |a Oncology. 
650 0 |a Cardiology. 
650 1 4 |a Proteins. 
650 2 4 |a Immunology. 
650 2 4 |a Cancer Biology. 
650 2 4 |a Medical Genetics. 
650 2 4 |a Oncology. 
650 2 4 |a Cardiology. 
700 1 |a Yuzhalin, Arseniy E.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9783034807944 
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