Glutamate-based Therapies for Psychiatric Disorders

Both metabotropic and ionotropic glutamate receptors present attractive "druggable" targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injur...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Skolnick, Phil (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2010.
Edición:1st ed. 2010.
Colección:Milestones in Drug Therapy,
Temas:
Psychiatry.
Pharmacology.
Neurosciences.
Neuroscience.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • N-Methyl-d-Aspartate (NMDA) Antagonists for the Treatment of Depression
  • Ionic Glutamate Modulators in Depression (Zinc, Magnesium)
  • Positive Allosteric Modulation of AMPA Receptors: A Novel Potential Antidepressant Therapy
  • Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors
  • Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders
  • Activation of Group II Metabotropic Glutamate Receptors (mGluR2 and mGluR3) as a Novel Approach for Treatment of Schizophrenia
  • mGluR1 Negative Allosteric Modulators: An Alternative Metabotropic Approach for the Treatment of Schizophrenia
  • Metabotropic Glutamate Receptors as Targets for the Treatment of Drug and Alcohol Dependence
  • Metabotropic Approaches to Anxiety.

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