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Handbook of HER2-targeted agents in breast cancer

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year.  Of these cases, approximately  15-25% overexpress HER2, a transmembrane RTK kinase that is associated with aggress...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Alvarez, Ricardo H. (Autor), Cortés, Javier (Autor), Mattos-Arruda, Leticia (Autor), Falzon, Mary (Autor), Fasolo, Angelica (Autor), Gandy, Michael (Autor), Gianni, Luca (Autor), Harbeck, Nadia (Autor), Piccart, Martine (Autor), Zambelli, Stefania (Autor), Zardavas, Dimitrios (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tarporley : Springer Healthcare Ltd. : Imprint: Springer Healthcare, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo

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100 1 |a Alvarez, Ricardo H.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
245 1 0 |a Handbook of HER2-targeted agents in breast cancer  |h [electronic resource] /  |c by Ricardo H Alvarez, Javier Cortés, Leticia Mattos-Arruda, Mary Falzon, Angelica Fasolo, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart, Stefania Zambelli, Dimitrios Zardavas. 
250 |a 1st ed. 2013. 
264 1 |a Tarporley :  |b Springer Healthcare Ltd. :  |b Imprint: Springer Healthcare,  |c 2013. 
300 |a XI, 96 p. 13 illus.  |b online resource. 
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505 0 |a Introduction and background biology -- HER2 testing -- HER2-positive breast cancer: adjuvant and neoadjuvant therapy -- HER2-positive metastatic breast cancer: first-line treatment -- HER2-positive metastatic breast cancer: second-line treatment -- Emerging targeted agents for HER2-positive breast cancer. 
520 |a Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year.  Of these cases, approximately  15-25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes.  However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer  provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings. 
650 0 |a Oncology. 
650 0 |a Primary care (Medicine). 
650 0 |a Family medicine. 
650 0 |a Internal medicine. 
650 0 |a Therapeutics. 
650 1 4 |a Oncology. 
650 2 4 |a Primary Care Medicine. 
650 2 4 |a General Practice and Family Medicine. 
650 2 4 |a Internal Medicine. 
650 2 4 |a Therapeutics. 
700 1 |a Cortés, Javier.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Mattos-Arruda, Leticia.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Falzon, Mary.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Fasolo, Angelica.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Gandy, Michael.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Gianni, Luca.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Harbeck, Nadia.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Piccart, Martine.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Zambelli, Stefania.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
700 1 |a Zardavas, Dimitrios.  |e author.  |4 aut  |4 http://id.loc.gov/vocabulary/relators/aut 
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950 |a Medicine (SpringerNature-11650) 
950 |a Medicine (R0) (SpringerNature-43714)