Translational Stem Cell Research Issues Beyond the Debate on the Moral Status of the Human Embryo /

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hug, Kristina (Editor ), Hermerén, Göran (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edición:1st ed. 2011.
Colección:Stem Cell Biology and Regenerative Medicine,
Temas:
Stem cells.
Stem Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • PREFACE
  • BIOSKETCHES
  • SECTION I: TRANSLATIONAL STEM CELL RESEARCH: WHAT IS POSSIBLE TODAY AND WHAT STILL REMAINS TO BE ACHIEVED?- Chapter 1. Towards clinical application of stem cells in neurodegenerative disorders (Olle Lindvall and Zaal Kokaia)
  • Chapter 2. Treating cardiac disorders with stem cells (Christine Mummery)
  • Chapter 3. Treating diabetes (Mattias Hansson and Ole D. Madsen)
  • Chapter 4. Treating oncologic diseases (Peter W. Andrews)
  • Chapter 5. Clinical application of autologous epithelial stem cells in disorders of squamous epithelia (Nicolas Grasset and Yann Barrandon)
  • Chapter 6. Towards a cell therapy for Muscular Dystrophy: technical and ethical issues (Giulio Cossu)
  • Chapter 7. Towards modelling and therapy of genetic diseases using pluripotent stem cells (Petr Dvorak)
  • Chapter 8. Therapeutic possibilities of induced pluripotent stem cells (Harold Ayetey)
  • Chapter 9. Industrial applications of stem cells (Oliver Brüstle, Michael Rossbach and Manal Bosnali)
  • Chapter 10. The obstacles on the road to clinical applications of stem cell-based therapies: What has been done to overcome these obstacles and what remains to be done? (Outi Hovatta)
  • SECTION II. TRANSLATING STEM CELL RESEARCH KNOWLEDGE FROM BENCH TO BEDSIDE: ETHICAL ISSUES
  • Chapter 11. Animal use in translational stem cell research and treatment development: Ethical issues (Kate Millar)
  • Chapter 12. Ethical aspects of stem cell-based clinical translation: research, innovation, and delivering unproven interventions (Jeremy Sugarman and Doug Sipp)
  • Chapter 13. Translational stem cell research in pediatrics: Ethical issues (Michael Fuchs)
  • Chapter 14. Experimental stem cell-based therapy in pediatrics: A fictional case study (Kristina Hug and Anders Castor)
  • SECTION III: CREATION OF HUMAN-ANIMAL ENTITIES FOR TRANSLATIONAL STEM CELL RESEARCH: SCIENTIFIC, ETHICAL AND REGULATORY CHALLENGES
  • Chapter 15. Creation of human-animal entities for translational stem cell research: Scientific explanation of issues that are often confused (Neville Cobbe and Val Wilson)
  • Chapter 16. Creation of human-animal entities for translational stem cell research: Ethical issues (Gisela Badura-Lotter and Marcus Duewell)
  • Chapter 17. Chimeras + hybrids = chimbrids: Legal aspects (Jochen Taupitz)
  • SECTION IV: STEM CELL BANKING FOR TRANSLATIONAL STEM CELL RESEARCH OR STEM CELL-BASED THERAPIES
  • Chapter 18. Stem cell banks: Reality, roles and challenges (Glyn Stacey)
  • Chapter 19. Broad consent (Linus Broström and Mats Johansson)
  • Chapter 20. Banks, repositories and registries of stem cell lines: The challenges to legal regulation (Mette Hartlev)
  • SECTION V: TRANSLATIONAL STEM CELL RESEARCH AND COMMERCIAL FUNDING
  • Chapter 21. Proprietary interests and collaboration in stem cell science: Avoiding anticommons, countering canalization (Matthew Herder)
  • SECTION VI: PATENTING OF HUMAN STEM CELL-BASED INVENTIONS: SCIENTIFIC, ETHICAL AND REGULATORY ISSUES
  • Chapter 22. Legal problems raised by patents on human stem cell-based inventions (Paul L.C. Torremans)
  • Chapter 23. Patenting of human stem cell-based inventions: Can there be technological solutions to a moral dilemma? (Aliki Nichogiannopoulou)
  • Chapter 24. Patenting of human stem cell-based inventions: Ethical issues including and beyond the morality clause (Göran Hermerén)
  • SECTION VII: FROM GENERAL PUBLIC TO RESEARCHERS, AND VICE VERSA: COMMUNICATION ISSUES IN TRANSLATIONAL STEM CELL RESEARCH
  • Chapter 25. Ethical, legal and social implications of translational stem cell research: Effects of commercialisation on public opinion and trust of stem cell research (Ubaka Ogbogu and Amy Zarzeczny)
  • Chapter 26. Patients' organisations and their opinions: How much have they been taken into consideration when regulating stem cell research? (Mary Baker and Philip Watson)
  • Chapter 27. Communicating translational stem cell research to the general public: Challenges and suggestions (Sébastien Duprat)
  • SECTION VIII: TRANSLATIONAL STEM CELL RESEARCH AND ITS PSYCHOLOGICAL IMPLICATIONS
  • Chapter 28. Psychosocial and cultural factors affecting judgments and decisions about translational stem cell research (Melissa L. Finucane and Andrew E. Williams)
  • SECTION IX: ETHICAL EVALUATION OF TRANSLATIONAL STEM CELL RESEARCH PROJECTS IN RESEARCH ETHICS COMMITTEES
  • Chapter 29. Ethics and uncertainty: Considerations for the design and review of translational trials involving stem cells (James Anderson and Jonathan Kimmelman)
  • SECTION X: LOOKING AT THE FUTURE OF TRANSLATIONAL STEM CELL RESEARCH AND STEM CELL-BASED THERAPEUTIC APPLICATIONS: RISKS, LONG-TERM EFFECTS AND PRIORITY SETTING
  • Chapter 30. Unruhe und Ungeweissenheit - Stem cells and risks (Nils-Eric Sahlin, Johannes Persson and Niklas Vareman)
  • Chapter 31. Looking at the future of translational stem cell research and stem cell-based therapeutic applications: Priority setting and social justice (Göran Hermerén).

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