Targeted Therapies Mechanisms of Resistance /

This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included.  Targeted Therapies: Mechanisms of Resistan...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gioeli, Daniel (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2011.
Edición:1st ed. 2011.
Colección:Molecular and Translational Medicine,
Temas:
Oncology.
Medicine-Research.
Biology-Research.
Cancer.
Biomedical Research.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Resistance to Targeted Therapies As a Result of Mutation(s) in the Target.- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies.- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry.-  Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications.-  Using Phosphoflow to Study Signaling Events of Sub Populations Resistant to Current Therapies
  • Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance Mathematical and Computational Models in Cancer
  • Somatic Evolution of Acquired Drug Resistance in Cancer
  • Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer
  • MicroRNA: A Potential Therapy Able to Target Multiple Cancer Pathways
  • Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance.

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