New Strategies in Stroke Intervention Ionic Transporters, Pumps, and New Channels /

Ischemic brain damage represents a major source of morbidity and mortality in westernized society and poses a significant financial burden on the health care system. To date, few effective therapies have been realized to treat stroke and promising avenues have not proven clinically useful. Recent ev...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Annunziato, Lucio (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2010.
Edición:1st ed. 2010.
Colección:Contemporary Neuroscience
Temas:
Neurosciences.
Neurology .
Cardiology.
Medicine > Research.
Biology > Research.
Pharmacology.
Anesthesiology.
Neuroscience.
Neurology.
Biomedical Research.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Basis of Ionic Dysregulation in Cerebral Ischemia
  • Why have Ionotropic and Metabotropic Glutamate Antagonists Failed in Stroke Therapy?
  • Mitochondrial Channels as Potential Targets for Pharmacological Strategies in Brain Ischemia
  • Endoplasmic Reticulum Calcium Homeostasis and Neuronal Pathophysiology of Stroke
  • The Na + /Ca 2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia
  • The "Loop" Diuretic Drug Bumetanide-Sensitive Na + -K + -Cl - Cotransporter in Cerebral Ischemia
  • The Na + /H + Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia
  • The Na + /K + -ATPase as a Drug Target for Ischemic Stroke
  • Acid-Sensing Ion Channels (ASICs): New Targets in Stroke Treatment
  • Role of TRPM7 in Ischemic CNS Injury
  • Subtypes of Voltage-Gated Ca 2+ Channels and Ischemic Brain Injury
  • The Diverse Roles of K + Channels in Brain Ischemia
  • Clinical Trials with Drugs Targeting Ionic Channels, Antiporters, and Pumps in Ischemic Stroke.

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