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Visual Dysfunction in Diabetes The Science of Patient Impairment and Health Care /

An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement is designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retino...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Tombran-Tink, Joyce (Editor ), Barnstable, Colin J. (Editor ), Gardner, Thomas W. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2012.
Edición:1st ed. 2012.
Colección:Ophthalmology Research
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction
  • Diabetic Retinopathy - what we know, don't know, and need to know.- A Patient's viewpoint.- What patients with diabetes see-and don't see: subjective and objective visual function changes.- How do I know I have diabetic retinopathy - a clinician's view?.- Epidemiology & Economics.- Correlation between the presence and severity of diabetic retinopathy in families with diabetes.- Increasing public awareness of the diabetes endemic.- Nutrition and diabetes.- Diabetic retinopathy screening - progress and complications.- Measurements of retinal blood flow, vascular leakage, and oxygenation.- Optical imaging - Confocal microscopy to detect retinal vasculature.- Structural imaging - OCT.- Functional imaging - ERG.- Clinical phenotypes (reclassification).- Vascular changes.- Neuronal changes.- Inflammatory changes.- Other Ocular Complications of Diabetes.- New insights in the pathogenesis of diabetic retinopathy using a proteomic approach - Retina.- Vitreous proteomics.- Genomics.- Genome-wide linkage analyses to identify Loci for diabetic retinopathy.- Risk Factors.- Diabetic retinopathy correlates with increased incidence of cardiovascular events.- Pregnancy and rate of progression of diabetic retinopathy.- Molecular Mechanisms that Could Trigger Visual Dysfunction in Diabetes
  • Introduction.- Inflammation in the early pathogenesis of diabetic retinopathy -beauty and beast.- Oxidative stress and diabetic retinopathy.- Glucose induced cellular signaling in diab etic retinopathy.- The AGE/RAGE axis in early diabetic retinopathy.- Proteases and the retinal vasculature (and maybe the whole retina!).- IGFBP3 and retinal vessel growth.- PEDF, VEGF, CTGF review.- A decrease in the expression of somatostatin is an early event in diabetic retinopathy.- Connective tissue and connective tissue growth factor in diabetic retinopathy.- Molecular regulation of endothelial cell tight junctions and the blood retinal barrier.- Pericytes and diabetic retinopathy.- Leukostasis.- Adhesion molecules (ICAM-1 and VCAM-1) and diabetic retinopathy in type 2 diabetes.- Azurocidin as a Permeability Factor in the Retina.- Retinal arteriolar hemodynamic response to a combined isocapnic hyperoxia and glucose
  • Provocation in early sight-threatening diabetic retinopathy.- Urinary 8-hydroxydeoxyguanosine (8-OHdG) levels in diabetic retinopathy patients.- Tyrosine nitration in the molecular mechanisms of diabetic retinopathy.