Cargando…

Chemokine Receptors in Cancer

Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established tha...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Fulton, Amy M. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2009.
Edición:1st ed. 2009.
Colección:Cancer Drug Discovery and Development,
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-60327-267-4
003 DE-He213
005 20220116075442.0
007 cr nn 008mamaa
008 100301s2009 xxu| s |||| 0|eng d
020 |a 9781603272674  |9 978-1-60327-267-4 
024 7 |a 10.1007/978-1-60327-267-4  |2 doi 
050 4 |a RC261-271 
072 7 |a MJCL  |2 bicssc 
072 7 |a MED062000  |2 bisacsh 
072 7 |a MJCL  |2 thema 
082 0 4 |a 571.978  |2 23 
082 0 4 |a 616.994  |2 23 
245 1 0 |a Chemokine Receptors in Cancer  |h [electronic resource] /  |c edited by Amy M. Fulton. 
250 |a 1st ed. 2009. 
264 1 |a Totowa, NJ :  |b Humana Press :  |b Imprint: Humana,  |c 2009. 
300 |a VIII, 172 p. 13 illus.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Cancer Drug Discovery and Development,  |x 2196-9914 
505 0 |a Chemokines and Chemokine Receptors in Cancer Progression -- CXCR4 and Cancer -- HIF-1 Regulation of Chemokine Receptor Expression -- Chemokine Receptors Involved in Colon Cancer Progression, and Lymph Node Metastasis -- The CXCR3/CXCL3 Axis in Cancer -- Roles for CCR7 in Cancer Biology -- The CCL5/CCR5 Axis in Cancer -- CXC Chemokines in Cancer Angiogenesis -- The Roles of Chemokines and Chemokine Receptors in Prostate Cancer. 
520 |a Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established that most malignant cells also express one or more chemokine receptor. This book describes our current understanding regarding how chemokine receptors contribute to tumor cell migration as well as cell survival and proliferation. The function of chemokine receptors expressed on host cells including antitumor immune effector cells as well as angiostatic and angiogeneic functions of chemokines acting on endothelial cells are described. The role of chemokine receptors that act as decoy receptors is also summarized. The therapeutic potential and challenges of targeting chemokine receptors or cognate ligands is also addressed. 
650 0 |a Cancer. 
650 0 |a Oncology. 
650 1 4 |a Cancer Biology. 
650 2 4 |a Oncology. 
700 1 |a Fulton, Amy M.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781607610991 
776 0 8 |i Printed edition:  |z 9781617378850 
776 0 8 |i Printed edition:  |z 9781603272667 
830 0 |a Cancer Drug Discovery and Development,  |x 2196-9914 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-60327-267-4  |z Texto Completo 
912 |a ZDB-2-SME 
912 |a ZDB-2-SXM 
950 |a Medicine (SpringerNature-11650) 
950 |a Medicine (R0) (SpringerNature-43714)