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BLyS Ligands and Receptors

The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiati...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Cancro, Michael P. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2010.
Edición:1st ed. 2010.
Colección:Contemporary Immunology
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • The Beautiful Structures of BAFF, APRIL, and Their Receptors
  • BAFF Receptor Regulation of Peripheral B-Lymphocyte Survival and Development
  • Regulation of B-Cell Self-Tolerance By BAFF and the Molecular Basis of Its Action
  • Role of BAFF and APRIL in Antibody Production and Diversification
  • Signal Transduction by Receptors for BAFF and APRIL
  • TACI Signaling and Its Role in Immunity
  • The BAFF/APRIL System in Autoimmunity
  • Systemic Immune-Based Rheumatic Diseases: Blissless States of BLySfulness
  • The Role of BAFF and APRIL in Regulating Human B-Cell Behaviour: Implications for Disease Pathogenesis
  • Translation of BAFF Inhibition from Mouse to Non-human Primate and Human
  • BLyS/BR3 Receptor Signaling in the Biology and Pathophysiology of Aggressive B-Cell Lymphomas
  • Tipping the Scales of Survival: The Role of BLyS in B-Cell Malignancies.