Introduction to Systems Biology

Introduction to Systems Biology is an introductory text for undergraduate and graduate students who are interested in comprehensive biological systems. The authors provide a broad overview of the field using key examples and typical approaches to experimental design. The volume begins with an introd...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Choi, Sangdun (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2007.
Edición:1st ed. 2007.
Temas:
Life sciences.
Pharmacology.
Cytology.
Biochemistry.
Biophysics.
Developmental biology.
Life Sciences.
Cell Biology.
Bioanalysis and Bioimaging.
Developmental Biology and Stem Cells.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Scientific Challenges in Systems Biology
  • Bringing Genomes to Life: The Use of Genome-Scale In Silico Models
  • From Gene Expression to Metabolic Fluxes
  • Experimental Techniques for Systems Biology
  • Handling and Interpreting Gene Groups
  • The Dynamic Transcriptome of Mice
  • Dissecting Transcriptional Control Networks
  • Reconstruction and Structural Analysis of Metabolic and Regulatory Networks
  • Cross-Species Comparison Using Expression Data
  • Methods for Protein-Protein Interaction Analysis
  • Genome-Scale Assessment of Phenotypic Changes During Adaptive Evolution
  • Location Proteomics
  • Theoretical and Modeling Techniques
  • Reconstructing Transcriptional Networks Using Gene Expression Profiling and Bayesian State-Space Models
  • Modeling Spatiotemporal Dynamics of Multicellular Signaling
  • Kinetics of Dimension-Restricted Conditions
  • Mechanisms Generating Ultrasensitivity, Bistability, and Oscillations in Signal Transduction
  • Employing Systems Biology to Quantify Receptor Tyrosine Kinase Signaling in Time and Space
  • Dynamic Instabilities Within Living Neutrophils
  • Efficiency, Robustness, and Stochasticity of Gene Regulatory Networks in Systems Biology: ? Switch as a Working Example
  • Applications, Representation, and Management of Signaling Pathway Information: Introduction to the SigPath Project
  • Methods and Software Platforms for Systems Biology
  • SBML Models and MathSBML
  • CellDesigner: A Graphical Biological Network Editor and Workbench Interfacing Simulator
  • DBRF-MEGN Method: An Algorithm for Inferring Gene Regulatory Networks from Large-Scale Gene Expression Profiles
  • Systematic Determination of Biological Network Topology: Nonintegral Connectivity Method (NICM)
  • Storing, Searching, and Disseminating Experimental Proteomics Data
  • Representing and Analyzing Biochemical Networks Using BioMaze.

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