Transforming Growth Factor-Beta in Cancer Therapy, Volume II Cancer Treatment and Therapy /

Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provides a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The second volume, Cancer Treatment and Therapy, is divided into three parts. Part I examines transforming growth...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Jakowlew, Sonia B. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2008.
Edición:1st ed. 2008.
Colección:Cancer Drug Discovery and Development,
Temas:
Oncology.
Cancer.
Cytology.
Pathology.
Cancer Biology.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Transforming Growth Factor-? In Developing and Advanced Cancers
  • Transforming Growth Factor-? Signaling in Pancreas Development and Pancreatic Disease
  • Role of Transforming Growth Factor-? in the Pathogenesis of Human Head and Neck Squamous Cell Carcinoma
  • TGF-?, Smads and Cervical Cancer
  • TGF-? Signaling and Biglycan in Pancreatic Cancer
  • TGF-? Signaling in Endometrial Cancer
  • TGF-? Ligands, TGF-? Receptors, and Lung Cancer
  • Role of TGF-? in Osteolytic Bone Metastases
  • Hormonal Regulation of Transforming Growth Factor-? in Breast Cancer
  • TGF-? and Progression of Esophageal Cancer
  • TGF-? and HER2/ErbB2 and Breast Cancer Progression
  • TGF-? Dependent T-Cell Regulation in Colitis and Colon Cancer
  • Role of Transforming Growth Factor-? in the Kidney - Physiology and Pathology
  • Perturbations of TGF-? Signaling in Leukocytes as Drivers of Leukemogenesis and Epithelial Tumorigenesis
  • Transforming Growth Factor-? in Brain Functions and Dysfunctions
  • Inhibition of TGF-? Signaling in Multiple Myeloma and Its Bone Marrow Microenvironment
  • Key Roles of TGF-? and Smad3 in Prostate Cancer
  • Smad Signaling in Leukemic Growth and Differentiation: Crosstalk Between Smad and Multiple Pathways Through Activation of the TGF-? Type I Receptor
  • Transforming Growth Factor-? in Cancer Treatment and Therapy
  • High-Throughput Screening of Protein Interaction Networks in the TGF? Interactome: Understanding the Signaling Mechanisms Driving Tumor Progression
  • Tumor Suppressor and Pro-progression Roles for TGF-? in Breast Cancer
  • Tumor Suppressors p53 and TGF? Converge to Regulate the Alpha-Fetoprotein Oncodevelopmental Tumor Marker
  • TGF?: Roles in DNA Damage Responses
  • The Rationale for and Effects of Targeting TGF-? for Glioma Therapy
  • Tumor Suppressor Functions of TGF?1 in T Cells
  • Therapeutic Effects of Adenovirus-Mediated Gene Transfer of TGF-? Signal Antagonists on Undesirable Epithelial-Mesenchymal Transition and Neovascularization
  • Role of TGF-? in Tumor Protection and Antitumor Immunity
  • Regulation of Angiogenesis and Tumor Growth by Thrombospondin-1
  • Cancer-Associated Fibroblasts and the Role of TGF-?
  • Adoptive Transfer of Tumor Reactive TGF-? Insensitive CD8+ T-cells for Cancer Therapy
  • DNA Methylation and Histone Deacetylation Inhibitors as Potential Therapeutic Agents for the Reconstitution of TGF-? Signaling in Breast Cancer
  • Reactive Stroma and Evolution of Tumors: Integration of Transforming Growth Factor-?, Connective Tissue Growth Factor, and Fibroblast Growth Factor-2 Activities
  • TGF-? Signaling and Vascular Morphogenesis
  • Aberrant Transforming Growth Factor-? Signaling in Human Pancreatic Cancer: Translational Implications
  • TGF-? and Stromal Influences Over Local Tumor Invasion
  • TGF-? at the Crossroads Between Inflammation, Suppression and Cancer
  • Development of Inhibitors of Transforming Growth Factor-? Signaling for Therapy
  • Transforming Growth Factor-? (TGF-?) Signaling Inhibitors in Cancer Therapy
  • Targeting TGF-? as a Strategy to Ameliorate Intestinal Side Effects of Radiation Therapy
  • Targeting Transforming Growth Factor-? in Metastasis: In Vitro and In Vivo Mechanisms
  • Targeted Downregulation of TGF-?2 with AP 12009 in Tumor Therapy
  • Modulating TGF-? Receptor Signaling: A Novel Approach of Cancer Therapy
  • Engineering TGF-? Traps: Artificially Dimerized Receptor Ectodomains as High-affinity Blockers of TGF-? Action
  • The Use of Virtual Screening in ALK5 Kinase Inhibitor Discovery and Validation of Orally Active ALK5 Kinase Inhibitors in Oncology
  • Soluble Type II Transforming Growth Factor-? Receptor Inhibits Tumorigenesis by Augmenting Host Antitumor Immunity
  • Reversal of EMT by Small-Molecule Inhibitors of TGF-? Type I and II Receptors: Implications for Carcinoma Treatment
  • Soluble TGF-? Type III Receptor Suppresses Malignant Progression of Human Cancer Cells
  • Targeting Smad-Dependent TGF-? Signaling with Peptide Aptamers
  • Rationale for Anti-TGF-? Antibody Therapy in Oncology.

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