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Transforming Growth Factor-Beta in Cancer Therapy, Volume I Basic and Clinical Biology /
Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of trans...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2008.
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| Edición: | 1st ed. 2008. |
| Colección: | Cancer Drug Discovery and Development,
|
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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|---|---|---|---|
| 001 | 978-1-59745-292-2 | ||
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| 020 | |a 9781597452922 |9 978-1-59745-292-2 | ||
| 024 | 7 | |a 10.1007/978-1-59745-292-2 |2 doi | |
| 050 | 4 | |a RC254-282 | |
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| 072 | 7 | |a MJCL |2 thema | |
| 082 | 0 | 4 | |a 616.994 |2 23 |
| 245 | 1 | 0 | |a Transforming Growth Factor-Beta in Cancer Therapy, Volume I |h [electronic resource] : |b Basic and Clinical Biology / |c edited by Sonia B. Jakowlew. |
| 250 | |a 1st ed. 2008. | ||
| 264 | 1 | |a Totowa, NJ : |b Humana Press : |b Imprint: Humana, |c 2008. | |
| 300 | |a XXIV, 735 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 1 | |a Cancer Drug Discovery and Development, |x 2196-9914 | |
| 505 | 0 | |a Basic Concepts of TGF-? Signaling in Normal Physiology and Cancer Pathobiology -- Component Hardware for Transforming Growth Factor-? Signal Transduction: TGF-? Ligands, TGF-? Receptors, and Smads -- TGF-? Signaling in Homeostasis and Cancer -- TGF-? Availability: Latent TGF-? and Latent TGF-? Binding Proteins -- Biological Functions of Latent TGF-?-Binding Proteins and Activation of TGF-? -- Regulators of Smad2/3 Transcription and Phosphorylation -- Interaction of Smad4 and Embryonic Liver Fodrin-?-spectrin in Hyperplasia, Neoplasia, and Tumor Suppression -- Regulation of Smad Activity by Phosphorylation -- Nuclear Targeting of TGF-?-Activated Smads in Normal and Tumor Biology -- Ski, SnoN, and Akt as Negative Regulators of Smad Activity: Balancing Cell Death and Cell Survival -- Transforming Growth Factor-? in Cancer Therapy: Smurfs in TGF-? Signaling and Regulation of Bone Homeostasis and Cancer -- Involvement of km23 Dynein Light Chains in TGF ? Signaling -- TGF-? Signaling in Fibroblastic Cells and Oncogenesis -- Mechanisms of TGF-?-Induced Apoptosis in Cancer Cells -- Mechanisms of Cell Cycle Regulation by TGF-? Disabled in Cancer -- Transforming Growth Factor-? in Cancer Therapy -- TGF-? and Smad Signaling in Transcriptome Reprogramming During EMT -- Functional Interactions Between MMPs and TGF-? in Normal and Tumor Tissue -- Cooperation Between TGF-? and Wnt Pathway Components in Regulating Mesenchymal Stem Cell Function -- Interaction of Oncogenic Ras and TGF?1 Signaling in Cancer: Lessons From the Multistage Skin Carcinogenesis Model -- TGF-? Superfamily Members in Normal and Tumor Biology -- Proteomics Analysis of TGF? Superfamily Members -- Mullerian Inhibiting Substance: A Potential Nontoxic, Naturally Occurring Therapeutic Agent for Certain Human Cancers -- Activins, Inhibins, and Bone Morphogenetic Proteins as Modulators and Biomarkers of Prostate Cancer Progression -- Bone Morphogenic Proteins and Angiogenesis in Developing Tumors -- Histone Methyltransferase and Smad Interactions in BMP Signaling -- Endoglin (CD105): A Strong Candidate for Immunologic Targeting of Tumor Neovasculature in Human Malignancies -- Activins and Inhibins in Cancer Progression -- Bone Morphogenetic Proteins/Growth Differentiation Factors and Smad Activation in Ovarian Granulosa Cells and Carcinoma -- Regulation of the Transforming Growth Factor-? Superfamily by Betaglycan -- Uterine Sensitization Associated Gene-1: A Bone Morphogenetic Protein Antagonist with a Role in Kidney -- Role of Betaig-h3 Gene in Carcinogenesis -- Activins and the Liver -- Myostatin Signaling in Normal and Tumor Cells -- TGF-? in Inflammation and Fibrosis -- Triterpenoids, Vitamin D, and TGF-?/Smad Signaling in Inflammation and Cancer -- Thrombospondin-Dependent Activation of Latent TGF-? in Fibrosis and Disease -- TGF-? in Pulmonary Fibrosis -- The Role of TGF-? in Bleomycin Induced Pulmonary Fibrosis -- Smads in the Fibrotic Response: Findings in the Smad3 Knockout Mouse -- TGF-? Signaling in Renal Fibrosis and Inflammation: Gene Therapy Using Ultrasound-Microbubble-Mediated Inducible Smad7 -- Transforming Growth Factor-? Peptide Signaling in Pulmonary Development, Bronchopulmonary Dysplasia, Fibrosis, and Emphysema -- The Role of TGF-? in Radiation and Chemotherapy Induced Pulmonary Fibrosis: Inhibition of TGF-? as a Novel Therapeutic Strategy -- Negative Regulation of the TGF-? Family Signal Pathway by Inhibitory Smads and Their Involvement in Cancer and Fibrosis -- TGF-?-Related Antifibrotic Strategies in the Eye -- Transforming Growth Factor-? in Cutaneous Tissue Repair -- Topical Application of TGF-?1 Peptide Inhibitors for the Therapy of Skin Fibrosis -- Overexpressed Truncated TGF-? Type II Receptor Inhibits Fibrotic Behavior of Keloid Fibroblasts In Vitro and Experimental Scar Formation In Vivo. | |
| 520 | |a Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide a compendium of findings about the role of transforming growth factor-ß (TGF-ß) in cancer treatment and therapy. The first volume, Basic and Clinical Biology, is divided into three parts. Part I presents basic concepts of transforming growth factor-ß signaling in normal physiology and cancer pathobiology. Part II investigates transforming growth factor-ß superfamily members in normal and tumor biology. Part III details transforming growth factor-ß in inflammation and fibrosis. This volume's companion, Cancer Treatment and Therapy, examines transforming growth factor-ß in several developing and advanced cancers and discusses methods of treatment and therapy. Together, Transforming Growth Factor-ß in Cancer Therapy, Volumes 1 and 2, provide researchers and clinicians with a comprehensive and cutting-edge reference for the findings about the role of transforming growth factor-ß in biology and cancer treatment. | ||
| 650 | 0 | |a Oncology. | |
| 650 | 0 | |a Cytology. | |
| 650 | 0 | |a Cancer. | |
| 650 | 0 | |a Pharmacology. | |
| 650 | 1 | 4 | |a Oncology. |
| 650 | 2 | 4 | |a Cell Biology. |
| 650 | 2 | 4 | |a Cancer Biology. |
| 650 | 2 | 4 | |a Pharmacology. |
| 700 | 1 | |a Jakowlew, Sonia B. |e editor. |4 edt |4 http://id.loc.gov/vocabulary/relators/edt | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781617377358 |
| 776 | 0 | 8 | |i Printed edition: |z 9781588297143 |
| 830 | 0 | |a Cancer Drug Discovery and Development, |x 2196-9914 | |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-1-59745-292-2 |z Texto Completo |
| 912 | |a ZDB-2-SME | ||
| 912 | |a ZDB-2-SXM | ||
| 950 | |a Medicine (SpringerNature-11650) | ||
| 950 | |a Medicine (R0) (SpringerNature-43714) | ||