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Checkpoint Responses in Cancer Therapy
Extensive research has uncovered a set of molecular surveillance mechanisms - commonly called "checkpoints" - which tightly monitor cell-cycle processes. Today's anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2008.
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| Edición: | 1st ed. 2008. |
| Colección: | Cancer Drug Discovery and Development,
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| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- RB-Pathway
- Targeting the p53/MDM2 Pathway for Cancer Therapy
- DNA Topoisomerases as Targets for the Chemotherapeutic Treatment of Cancer
- Targeting ATM/ATR in the DNA Damage Checkpoint
- Compounds that Abrogate the G2 Checkpoint
- CDK Inhibitors as Anticancer Agents
- CHFR as a Potential Anticancer Target
- Antimicrotubule Agents
- Kinesin Motor Inhibitors as Effective Anticancer Drugs
- Targeting the Spindle Checkpoint in Cancer Chemotherapy
- Antiproliferation Inhibitors Targeting Aurora Kinases
- Plks as Novel Targets for Cancer Drug Design
- Do Histone Deacetylase Inhibitors Target Cell Cycle Checkpoints that Monitor Heterochromatin Structure?.