Cargando…
Regulation of Gene Expression
Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advan...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Totowa, NJ :
Humana Press : Imprint: Humana,
2007.
|
| Edición: | 1st ed. 2007. |
| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
| LEADER | 00000nam a22000005i 4500 | ||
|---|---|---|---|
| 001 | 978-1-59745-228-1 | ||
| 003 | DE-He213 | ||
| 005 | 20220116002007.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 100301s2007 xxu| s |||| 0|eng d | ||
| 020 | |a 9781597452281 |9 978-1-59745-228-1 | ||
| 024 | 7 | |a 10.1007/978-1-59745-228-1 |2 doi | |
| 050 | 4 | |a QD415-436 | |
| 072 | 7 | |a PSB |2 bicssc | |
| 072 | 7 | |a SCI007000 |2 bisacsh | |
| 072 | 7 | |a PSB |2 thema | |
| 082 | 0 | 4 | |a 572 |2 23 |
| 100 | 1 | |a Perdew, Gary H. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Regulation of Gene Expression |h [electronic resource] / |c by Gary H. Perdew, Jack P. Vanden Heuvel, Jeffrey M. Peters. |
| 250 | |a 1st ed. 2007. | ||
| 264 | 1 | |a Totowa, NJ : |b Humana Press : |b Imprint: Humana, |c 2007. | |
| 300 | |a IX, 333 p. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 505 | 0 | |a Gene Expression Control At The Mrna Level -- Overview -- Messenger RNA Accumulation -- Transcript Profiling -- Transcriptional Regulation of Gene Expression -- Posttranscriptional Processing of Messenger RNA -- Regulation Of Protein Levels And Transcription Factor Function -- Overview -- Protein Synthesis and Turnover -- Proteomics -- Determination of Protein-Protein Interactions and the Motifs That Mediate Them -- Posttranslational Modifications -- Dissection of Signaling Pathways -- Use Of Transgenic And Knockout Mice To Study Gene Regulation -- Overview -- Production of Transgenic Animals -- Knockout Animals -- Isolation of Cells and Cell Lines From Transgenic and Knockout Animals. | |
| 520 | |a Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein. Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems. | ||
| 650 | 0 | |a Biochemistry. | |
| 650 | 0 | |a Pharmacology. | |
| 650 | 0 | |a Medical genetics. | |
| 650 | 1 | 4 | |a Biochemistry. |
| 650 | 2 | 4 | |a Pharmacology. |
| 650 | 2 | 4 | |a Medical Genetics. |
| 700 | 1 | |a Vanden Heuvel, Jack P. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 700 | 1 | |a Peters, Jeffrey M. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 710 | 2 | |a SpringerLink (Online service) | |
| 773 | 0 | |t Springer Nature eBook | |
| 776 | 0 | 8 | |i Printed edition: |z 9781627038089 |
| 776 | 0 | 8 | |i Printed edition: |z 9781588292650 |
| 856 | 4 | 0 | |u https://doi.uam.elogim.com/10.1007/978-1-59745-228-1 |z Texto Completo |
| 912 | |a ZDB-2-SBL | ||
| 912 | |a ZDB-2-SXB | ||
| 950 | |a Biomedical and Life Sciences (SpringerNature-11642) | ||
| 950 | |a Biomedical and Life Sciences (R0) (SpringerNature-43708) | ||