Histone Deacetylases Transcriptional Regulation and Other Cellular Functions /

The recent discoveries that established histone acetylation as a key regulatory mechanism for gene expression triggered a wave of interest in histone posttranslational modifications and led to the development of novel anticancer agents now in clinical trials. In Histone Deacetylases: Transcriptional...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Verdin, Eric (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2006.
Edición:1st ed. 2006.
Colección:Cancer Drug Discovery and Development,
Temas:
Cancer.
Cancer Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Class I Histone Deacetylases
  • Histone Deacetylase 1
  • Biochemistry of Multiprotein HDAC Complexes
  • The Biology of HDAC3
  • The Biology of HDAC8, a Unique Class I Histone Deacetylase
  • Class II Histone Deacetylases
  • Regulation of Muscle Gene Expression by Histone Deacetylases
  • The Class IIa Histone Deacetylases
  • Histone Deacetylases in the Response to Misfolded Proteins
  • Class III Histone Deacetylases
  • Evolution of Sirtuins From Archaea to Vertebrates
  • Structure of the Sir2 Family of NAD+-Dependent Histone/Protein Deacetylases
  • The Enzymology of SIR2 Proteins
  • The Class III Protein Deacetylases
  • Histone Deacetylase Inhibitors
  • HDAC Inhibitors
  • Cell Cycle Targets of Histone Deacetylase Inhibitors
  • HDAC Inhibitors.

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