From Melanocytes to Melanoma The Progression to Malignancy /

Melanoma offers an excellent model for cancer biology and an opportunity to understand the progression of a normal skin cell-the melanocyte-to malignancy. In From Melanocytes to Melanoma: The Progression to Malignancy, leading researchers and clinicians join forces to explain how skin cancer develop...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Hearing, Vincent J. (Editor ), Leong, Stanley P. L. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2006.
Edición:1st ed. 2006.
Temas:
Oncology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Melanocyte Development and Function
  • The Origin and Development of Neural Crest-Derived Melanocytes
  • MITF
  • MITF
  • Melanocytes and the Transcription Factor Sox10
  • Human Cutaneous Pigmentation
  • Melanocyte Distribution and Function in Human Skin
  • Melanocyte Transformation and Progression to Melanoma
  • Altered Signal Transduction in Melanoma
  • BRN2 in Melanocytic Cell Development, Differentiation, and Transformation
  • The Dynamic Roles of Cell-Surface Receptors in Melanoma Development
  • Familial Melanoma Genes, Melanocyte Immortalization, and Melanoma Initiation
  • Genetic Progression From Melanocyte to Malignant Melanoma
  • The Multiple Roles of the Oncogenic Protein SKI in Human Malignant Melanoma
  • RB/E2F Regulation and Dual Activity in the Melanocytic System
  • Melanoma Development and Pigment Cell Transformation
  • The Biology and Genetics of Melanoma
  • The Biology of Xeroderma Pigmentosum
  • Divergent Pathways to Cutaneous Melanoma
  • Pigmentation, DNA Repair, and Candidate Genes
  • Low-Penetrance Genotypes, Pigmentation Phenotypes, and Melanoma Etiology
  • The Biology of Melanoma Progression
  • Optical Imaging Analysis of Atypical Nevi and Melanoma
  • Proteomics Analysis of Melanoma Cell Lines and Cultured Melanocytes
  • Primary Invasive Melanoma to Metastatic Melanoma
  • Paradigm of Metastasis for Malignant Melanoma
  • Repair of UV-Induced DNA Damage and Melanoma Risk
  • High-Risk Factors for Melanoma Metastasis
  • Role of Melanoma Inhibitory Activity in Early Development of Malignant Melanoma
  • Role and Regulation of PAR-1 in Melanoma Progression
  • Molecular Mechanisms of Melanoma Metastasis
  • Overview of Tumor Progression in Melanoma
  • The Plasticity of Melanoma Cells and Associated Clinical Implications
  • The Clinical Use of Molecular Markers as Predictors of Disease Outcome and Response to Therapy in Malignant Melanoma
  • The Role of DCT/TYRP2 in Resistance of Melanoma Cells to Drugs and Radiation
  • How Melanoma Cells Evade Chemotherapy
  • Apoptosis in Melanoma
  • Role of Melanoma-Associated Antigens
  • Host Responses to Melanoma
  • Future Perspectives.

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