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Biomarkers in Breast Cancer

It is now well recognized that individualized cancer treatment planning, based on tumor characteristics specific to an individual's cancer, makes it easier to select those most likely to benefit from toxic cancer therapies and to avoid treating those least likely to benefit. In Biomarkers in Br...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gasparini, Giampietro (Editor ), Hayes, Daniel F. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Totowa, NJ : Humana Press : Imprint: Humana, 2006.
Edición:1st ed. 2006.
Colección:Cancer Drug Discovery and Development,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • General Topics
  • Guidelines for the Design of Clinical Studies for the Development and Validation of Therapeutically Relevant Biomarkers and Biomarker-Based Classification Systems
  • Analytical Aspects of Biomarker Immunoassays in Cancer Research
  • Tissue Microarrays
  • Assays for Gene Expression and Post-Translational Protein Abnormalities
  • Gene Expression Profiling with DNA Microarrays
  • Assays for DNA Abnormalities
  • Assays for Gene Amplification
  • Tissue Predictive Biomakers
  • Cell Kinetics
  • Urokinase-Type Plasminogen Activator and PAI-1
  • Predictive Value of c--erb-B2 for Endocrine Therapy and Chemotherapy in Breast Cancer
  • erb-B2 as a Therapeutic Target
  • The Epidermal Growth Factor Receptor Pathway as a Selective Molecular-Targeted Treatment in Human Breast Cancer
  • p53 as a Prognostic and Predictive Indicator
  • Predictive Biomarkers in Body Fluids
  • Occult Metastatic Cells in Breast Cancer Patients
  • Circulating HER2/neu
  • Circulating Vascular Endothelial Growth Factor
  • Detection of Early Tumor Dissemination in Patients With Breast Cancer
  • Future Directions
  • New Technologies/New Markers/New Challenges.