Discoidin Domain Receptors in Health and Disease

The interactions of cells with their surrounding extracellular matrix (ECM) plays a pivotal role in driving normal cell behavior, from development to tissue differentiation and function. At the cellular level, organ homeostasis depends on a productive communication between cells and ECM, which event...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Fridman, Rafael (Editor ), Huang, Paul H. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Temas:
Cancer.
Medical microbiology.
Clinical biochemistry.
Cytology.
Cancer Biology.
Medical Microbiology.
Medical Biochemistry.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Part I: Discoidin Domain Receptor biology and roles in physiology
  • DDRs: Binding properties, cell adhesion and modulation of integrin function
  • DDRs and collagen fibrillogenesis
  • DDR Structural Biology
  • DDR Mouse models
  • DDR in Invertebrates
  • Part II: Discoidin Domain Receptors in Cancer
  • Discoidin Domain Receptors and Disease
  • Discoidin Domain Receptors in Normal Mammary Development and Breast Cancer Progression
  • Discoidin Domain Receptors in Lung Cancer
  • DDRs in healthy and cancerous reproductive systems
  • Small Molecule Inhibitors of Discoidin Domain Receptors
  • Discoidin Domain Receptor Signaling Networks
  • Discoidin Domain Receptor Signaling and Pharmacological Inhibitors
  • Functions of DDR1 in epithelial cell differentiation
  • Part III: Discoidin Domain Receptors in other pathologies
  • Discoidin Domain Receptor 2 in Development of Osteoarthritis
  • DDR1 in Renal Function and Disease
  • Discoidin Domain Receptors in Liver Fibrosis
  • The role of DDRs in Atherosclerosis
  • Discoidin Domain Receptors in Cardiac Development.

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