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Molecular and Cellular Mechanobiology

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across differe...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Chien, Shu (Editor ), Engler, Adam J. (Editor ), Wang, Peter Yingxiao (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Colección:Physiology in Health and Disease,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Part 1. Mechanosensors
  • The Primary Cilium as a Strain Amplifying Microdomain for Mechanotransduction at the Cell Membrane
  • Vascular Endothelial Mechanosensors in Response to Fluid Shear Stress
  • Cadherins in Mechanotransduction
  • Perspectives of FRET Imaging to study Epigenetics and Mechanobiology in the Nucleus
  • Part 2. Transducers
  • Emerging Roles of YAP/TAZ in Mechanobiology
  • Role of Rho GTPases in Mechanobiology
  • Illuminating Cell Adhesion: Modern Microscopy Approaches to Study Integrin-Based Focal Adhesions
  • Part 3. Epigenetic and Genetic Regulations in the Nucleus
  • Mechanotransduction to Epigenetic Remodeling
  • The Nuclear Lamina: From Mechano-Sensing in Differentiation to Cancer Cell Migration
  • Role of Cell Geometry on Nuclear Mechanics, Chromosome Reorganization, and Gene Expression
  • Part 4. Applications
  • Mechanobiological Control of Cell Fate for Applications in Cardiovascular Regenerative Medicine
  • Heart Valve Mechanobiology in Development and Disease
  • Molecular and Cellular Mechanobiology of Cancer.