Cargando…

Regenerative Medicine for Degenerative Muscle Diseases

This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an arra...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Childers, Martin K. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Humana, 2016.
Edición:1st ed. 2016.
Colección:Stem Cell Biology and Regenerative Medicine,
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-1-4939-3228-3
003 DE-He213
005 20220120001906.0
007 cr nn 008mamaa
008 151218s2016 xxu| s |||| 0|eng d
020 |a 9781493932283  |9 978-1-4939-3228-3 
024 7 |a 10.1007/978-1-4939-3228-3  |2 doi 
050 4 |a QH588.S83 
072 7 |a PSC  |2 bicssc 
072 7 |a SCI017000  |2 bisacsh 
072 7 |a PSC  |2 thema 
082 0 4 |a 571.6  |2 23 
082 0 4 |a 616.02774  |2 23 
245 1 0 |a Regenerative Medicine for Degenerative Muscle Diseases  |h [electronic resource] /  |c edited by Martin K. Childers. 
250 |a 1st ed. 2016. 
264 1 |a New York, NY :  |b Springer New York :  |b Imprint: Humana,  |c 2016. 
300 |a XIII, 336 p. 26 illus., 23 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Stem Cell Biology and Regenerative Medicine,  |x 2196-8993 
505 0 |a Preface -- 1. Regenerative Medicine Approaches to Degenerative Muscle Diseases -- 2. An Overview of rAAV Vector Product Development for Gene Therapy -- 3. Gene Discovery in Congenital Myopathy -- 4. Stem Cell Transplantation for Degenerative Muscle -- 5. Spinal Cord Cellular Therapeutics Delivery:  Device Design Considerations -- 6. Patient Derived Induced Pluripotent Stem Cells Provide a Regenerative Medicine Platform for Duchenne Muscular Dystrophy Heart Failure -- 7. Overview of Chemistry, Manufacturing and Controls (CMC) for Pluripotent Stem Cell-Based Therapies -- 8. Regenerative Rehabilitation: Synergizing Regenerative Medicine Therapies with Rehabilitation for Improved Muscle Regeneration in Muscle Pathologies -- 9. Practical Nutrition Guidelines for Individuals with Duchenne Muscular Dystrophy -- 10. Identifying Beneficial Drug Therapies for Muscle Disease Using Zebrafish -- 11. The Use of miRNAs in Muscle Diseases -- 12 Canine Inherited Dystrophinopathies and Centronuclear Myopathies -- Index. 
520 |a This book compiles and explores cutting-edge research in degenerative skeletal disorders, such as Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based therapies and gene replacement therapy. Twelve expertly-authored chapters navigate the nuances of these treatments in an array of contexts and biological systems. The topics covered include: How are urine cells from a patient with Duchenne muscular dystrophy transformed into beating heart cells? What can reprogrammed cells tell us about heart muscle failure? What do gene mutations mean for those born with a muscle disease? How are manufacturing methods applied to human stem cells? Does therapeutic exercise benefit those patients who receive engineered limb muscle? Is there practical advice about nutrition to enhance muscle function for the Duchenne patient? Can microRNAs be useful to regenerate diseased muscle? Regenerative Medicine for Degenerative Muscle Diseases is ideal for scientists and clinicians from varying disciplines in genetics, cell biology, virology, cell-based manufacturing, rehabilitation medicine, nutrition, veterinary medicine and neurosurgery. The reader will see how transformative changes occur in medicine that can powerfully impact the future for patients suffering from inherited disorders affecting muscles of the body, including the heart. 
650 0 |a Stem cells. 
650 0 |a Biotechnology. 
650 1 4 |a Stem Cell Biology. 
650 2 4 |a Biotechnology. 
700 1 |a Childers, Martin K.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9781493932276 
776 0 8 |i Printed edition:  |z 9781493932290 
776 0 8 |i Printed edition:  |z 9781493980017 
830 0 |a Stem Cell Biology and Regenerative Medicine,  |x 2196-8993 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-1-4939-3228-3  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)