BRAF Targets in Melanoma Biological Mechanisms, Resistance, and Drug Discovery /

This volume contains a collection of writings from the leaders in the fields of Molecular Biology and Melanoma Research which will begin to tell the ever-expanding story of the most recent findings, discoveries, and potential of BRAF-directed targets in melanoma. Recent research has shown that BRAF...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Sullivan, Ryan J. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Humana, 2015.
Edición:1st ed. 2015.
Colección:Cancer Drug Discovery and Development, 82
Temas:
Cancer.
Medicine-Research.
Biology-Research.
Medical microbiology.
Pharmacology.
Cancer Biology.
Biomedical Research.
Medical Microbiology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Melanoma: Historical Context
  • Melanoma Pathogenesis
  • Molecular Diagnostics and Tumor Mutational Analysis
  • Clinical Utility of BRAF-targeted therapy in Melanoma
  • The Ethics of Randomized Trials in Oncology
  • Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma
  • Targeting the cell cycle and p53 in combination with BRAF-directed therapy
  • Combination BRAF-directed therapy and immunotherapy
  • Moving Forward: Making BRAF-Targeted Therapy Better.

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