Extrasynaptic GABAA Receptors

GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed "tonic" inhibition, has been described. Whereas synaptic GABAA receptors underlie classical "phasic" GABAA rec...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Errington, Adam C. (Editor ), Di Giovanni, Giuseppe (Editor ), Crunelli, Vincenzo (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:The Receptors, 27
Temas:
Neurosciences.
Pharmacology.
Neurology .
Neuroscience.
Neurology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • A brief introduction to extrasynaptic GABAA receptors and 'tonic' GABAA receptor mediated inhibition in physiology and disease
  • Extrasynaptic GABAA receptors: subunit composition, distribution, and regulation
  • Biophysical properties of recombinant 2- AND δ- subunit containing GABAA receptors
  • The pharmacology of extrasynaptic GABAA receptors
  • Neurosteroids and extrasynaptic GABAA receptors
  • Sources of GABA that activate extrasynaptic GABAA receptors
  • Modulation of Extrasynaptic GABAA Receptors by G-protein-coupled Receptors
  • Extrasynaptic GABAA receptors and tonic inhibition in spinal cord
  • The role of peri-synaptic GABA receptors after stroke
  • The role of extrasynaptic GABAA receptors in focal epilepsy
  • Gain-of-Function of Thalamic Extrasynaptic GABA-A Receptors in Typical Absence Seizures
  • GABAergic control of the hypothalamic-pituitary-adrenal (HPA) axis: role of extrasynaptic GABAA receptors
  • Tonic GABAA receptor mediated inhibition in Fragile-X Syndrome: A cause of dysfunction or a pathway for a cure?

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