Systems Biology of RNA Binding Proteins

After transcription in the nucleus, RNA binding proteins (RBPs) recognize cis-regulatory RNA elements within pre-mRNA sequence to form mRNA-protein (mRNP) complexes. Similarly to DNA binding proteins such as transcription factors that regulate gene expression by binding to DNA elements in the promot...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Yeo, Gene W. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Advances in Experimental Medicine and Biology, 825
Temas:
Bioinformatics.
Proteins .
Molecular genetics.
Computational and Systems Biology.
Protein Biochemistry.
Molecular Genetics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Encyclopedia of RNA binding protein expression and domain annotations
  • RNA localization and RNA binding proteins that control localization
  • Genome-wide approaches to studying alternative polyadenylation events and the RBPs that control them
  • RNA binding proteins, PRC complex and long ncRNAs
  • Gene and genome regulation by piwi proteins
  • Engineering Artificial RBP interactions
  • Querying functional polymorphisms by high throughput binding and functional assays
  • RNA binding protein networks in EMT/MET
  • Therapies against diseases associated with RNA processing defects and RNA binding proteins
  • Repeat-disorders and the RNA binding proteins implicated in them
  • RNA binding proteins in heart development
  • Identification of miRNAs and their targets in C elegans
  • Splicing code
  • Index.

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