Management of Castration Resistant Prostate Cancer

This volume provides new data about the molecular biology of CRPC and a review of the definition, staging and prognostic factors that define CRPC. The book features an in-depth review of proven therapeutic options, including bone-targeted therapies, immunotherapy, chemotherapy and hormonal based the...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Saad, Fred (Editor ), Eisenberger, Mario A. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York, NY : Springer New York : Imprint: Humana, 2014.
Edición:1st ed. 2014.
Colección:Current Clinical Urology,
Temas:
Urology.
Oncology.
Interventional radiology.
Interventional Radiology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction - Castration Resistant Prostate Cancer: A Rapidly Expanding Clinical State and a Model for New Therapeutic Opportunities
  • Evolution of Clinical States and the Castration Resistant Clinical Paradigm
  • Molecular Mechanisms of Prostate Cancer Progression after Castration
  • New Imaging Modalities
  • Androgen Receptor Biology in Castration Resistant Prostate Cancer
  • The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer
  • Approaches Targeting Androgen Synthesis (CYP 17 inhibitors)
  • Cytotoxic Chemotherapy (Taxanes and Taxane Combinations)
  • The Emerging Role of Immunotherapy in Castrate Resistant Prostate Cancer
  • Bone Targeted Therapy: Rationale and Current Status
  • Radium-223 and Other Radiopharmaceuticals in Prostate Cancer
  • Introduction
  • Phase I/II targeted treatments
  • Defining Clinical Endpoints in Castration-resistant Prostate Cancer
  • Angiogenesis Inhibition in Castration Resistant Prostate Cancer
  • Co-targeting Adaptive Survival Pathways
  • Targeting the PI3K/AKT/mTOR Pathway in Prostate Cancer
  • PARP Inhibitors
  • Targeting C-Met/VEGF in Castration Resistant Prostate Cancer
  • Epigenetics in Castration Resistant Prostate Cancer
  • Undifferentiated Prostate Cancer and the Neuroendocrine Phenotype
  • Strategies Addressing Quality of Life: Patient Reported Outcome and Symptoms Management
  • Evidence-Based Therapeutic Approaches for mCRPC patients: Rational Sequence of Standard Treatment Options and Design for Future Drug Development.

Ejemplares similares